Alzheimer's disease is an irreversible, progressive brain
disorder that occurs gradually over time and results in memory loss,
unusual behavior, personality changes and a decline in thinking
abilities. It affects more than 4 million Americans and many millions
across the globe.
However, the prevalence of Alzheimer's disease among adults
ages 70 to 79 in India is more than four times less than the rate
in the United States. Why such a significant difference? Some researchers
believe the answer for this drastic disparity in Alzheimer's
patients found in India is a direct result of curcumin, a yellow
pigment found in curry spice blocks used as a food dye and preservative.
Treating Alzheimer's With Curcumin
Curcumin has been part of Indian traditional medicine for thousands
of years, used as a safe anti-inflammatory treatment for a variety
of aliments.
According to a study involving genetically engineered mice, it
was suggested that curcumin could inhibit the accumulation of destructive
beta amyloids--a component of the neurofibrillary tangles and plaques
attributed to Alzheimer's disease--in the brains of Alzheimer's
patients, as well as break up existing plaques. Based on findings,
researchers determined:
-
Curcumin is more effective in inhibiting the formation of the
protein fragments than many other potential Alzheimer's
treatments
-
The low molecular weight and polar structure of curcumin allows
it to penetrate the blood-brain barrier effectively and bind
to beta amyloid
-
Alzheimer's symptoms caused by inflammation and oxidation
are eased by curcumin's powerful antioxidant and anti-inflammatory
properties
Medical
News Today December 29, 2004
|