Age-related cataract, a cataract that occurs in the elderly and
is characterized by an initial opacity in the lens, is an extremely
common disorder that has both substantial health and economic effects.
In fact, age-related cataract is the leading cause of blindness
in the world. Although the visual impairment associated with cataract
can be corrected surgically, it is at a major social cost, as cataract
removal is the most frequently performed surgical procedure among
Medicare patients, costing some $3.5 billion a year in the United
States.
This study examined the association between specific types of fat
in the diet, measured over a period of 10 to 15 years, and the development
of cataracts. This is the first published study to perform this
extensive type of dietary analysis with cataracts.
Polyunsaturated fats (PUFAs) are essential fats and consist of
omega-6 and omeg-3 fats. PUFAs have generally been considered to
be healthy elements of the diet. Linoleic acid is an 18-carbon omega
-- 6 PUFA. It is abundant in the Western diet and is the major fatty
acid in safflower, sunflower, corn, soybean and cottonseed oils,
as it accounts for more than 50 percent of the total fatty acid
content in these oils. Although linoleic acid is an essential fatty
acid, the consumption of modest amounts, equivalent to 1 percent
of total calories, is adequate to protect against essential fatty
acid deficiency.
Linoleic acid constitutes up to 0.5 percent of the total fatty
acids in the lens membrane. Because linoleic acid is prone to being
oxidized, increasing concentrations in the lens membrane may cause
free radical damage.
Linolenic acid is an 18-carbon omega -- 3 PUFA. Spelling wise there
is only a difference of one "n," but it makes all the
difference in the world. Linolenic acid is the omega-3 fat of vegetable
oils found in flax, walnuts and green leafy vegetables.
The researchers found that when the diet was increased with either
of these fats there was an increased risk of developing cataracts.
American
Journal of Clinical Nutrition April 2005;81(4):773-779
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