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Further research is needed on the effects of phthalates, chemicals
used to lengthen the life of fragrances and soften plastic in
toys and medical tubes, on children, according to an organization
of U.S. pediatricians.
Although no studies have been performed to determine human
toxicity from exposure to the chemicals, a previous study
found that some people have very high levels of phthalates
in their blood.
Further, past studies have linked the chemicals to birth
defects and other harmful effects in animals.
Two phthalates, DEHP and DINP, are of particular concern
because they are known to be toxic and sensitive populations
could potentially be exposed to them.
For instance, premature infants in intensive care units may
be exposed to DEHP in plastic medical tubing and bags.
The report calling for further studies on phthalates is aimed
at educating pediatricians about the risks to children from
chemical exposures, using phthalates as examples, and helping
them to determine and quantify such risks.
In 2002, the U.S. Food and Drug Administration (FDA) advised
that, if available, alternatives to phthalates should be used
to keep plastics soft because certain devices could expose
people to a toxic dose of DEHP.
The chemical might be found in IV bags and tubing, blood
bags, nasogastric tubes, dialysis bags and tubing, and other
tubing used to support and feed premature infants, according
to the FDA.
In 1999, the European Union banned the use of phthalates
from some products, such as baby toys. In the United States
and Canada the chemicals have been removed from infant bottle
nipples and other products intended to go in a baby’s
mouth, however the U.S. government has declined to ban the
use of phthalates.
Pediatrics
June 2003;111:1467-1472
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