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February 26 2003
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Pneumonia Vaccine Not as Effective as Thought

 

Killing more than 60,000 Americans each year, pneumonia is one of the top five killers of people aged 65 years and older.

The elderly often receive pneumonia immunizations, followed by a pneumonia vaccine booster shot five years later, to protect them for the disease. However, research has indicated that the booster shot does not protect people for life as was previously thought.

Initially it was thought that one shot of the pneumonia vaccine, first introduced in the 1980s, would protect a patient for life. Later studies found that this was not the case so experts recommended that high-risk patients get booster shots five years after the first vaccination.

However, in a study of 67 elderly individuals, it was found that even the booster shot does not offer complete protection. Researchers measured antibody levels after the participants had received an initial dose of the pneumococcal vaccine and then gave each individual a booster shot. Antibody levels were measured one month, six months and one year later.

Levels of the patients’ protective antibodies rose significantly one month after the booster shot, however by the end of the year levels had dropped to equal or below the starting points.

These results indicate that the vaccine no longer protected the participants after one year.

Researchers suggest the possibility of vaccinating high-risk patients every year or every other year, though the safety of administering pneumococcal shots to this population is not known. They also recommended that a more effective vaccine should be developed.

Elderly patients and others at high risk should talk to their doctors about getting a vaccination or a booster. The pneumococcal bacteria, which cause most pneumonias, can also spur blood infections such as meningitis. Many of these bacteria have become antibiotic-resistant, increasing their danger because they are more difficult to treat.

Journal American Geriatrics Society February 2003;51(2):240-5

References

[1] Richard Kent Zimmerman, MD, MPH. et.al. Routine Vaccines Across the Life Span, 2001. J of Fam. Pr. Oct. 2001,Vol. 50, No. 10.

[2] 138. US Department of Health and Human Services, Public Health Service: Healthy People 2000. Washington, DC, Government Printing Office, 1990

[3] http://www.census.gov/ population/ www/socdemo/ age/ppl-147.html

[4] AWP=Average Wholesale Price. List of Immunizing Agents and Average Wholesale Prices for 2002. PA Bulletin Doc. No. 02-1897. http:// www.medscape.com/ content/ 2002/00/44/19/ 441921/441921_tab.html


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