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September 18 2002
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The New Drug Push: Fish Oil + Lipitor For Your Cholesterol Levels

 

Who was studied?

The researchers studied about 50 men who were at risk for type 2 diabetes and showed signs of insulin resistance, a condition that occurs in pre-diabetic people. Type 2 diabetes is the most common form of diabetes, and occurs when the body can't properly use insulin. The men also had high levels of triglycerides and LDL cholesterol, and low levels of HDL cholesterol.

How was the study conducted?

There were four daily regimens that lasted 6 weeks:

  • Cholesterol-lowering drug Lipitor and fish oil tablets
  • Lipitor and a placebo
  • Fish oil tablets and a placebo
  • Two inactive placebos

None of the regimens improved insulin resistance, both statins and fish oil improved the men's balance of blood fats.

How did the statin therapy and fish oil work?

  • Statin therapy: This blocked the formation of cholesterol, which improved the clearance of molecules called ApoB that carry the harmful form of cholesterol in the blood.
  • Fish oils: These interrupted the making of triglycerides, which interfered with the liver's production of a certain type of ApoB molecules.

Diabetes August 2002;51:2377-2386



Dr. Mercola Dr. Mercola's Comments:

Adding fish oils to Lipitor will improve the risk for heart disease. However, lowering your insulin levels will achieve the same objective. The real issue is: Does one even need Lipitor?

My experience is that only a few people who have cholesterol levels above 350 would benefit from taking Lipitor. Nearly everyone else can control her cholesterol by following the eating plan. Adding fish oil to your diet will provide considerable additional benefits and further reduce your risk for heart disease. For the vast majority of people, fish oil will provide more benefits than taking Lipitor.

In many ways, this reminds me of the push of the progression of the treatment of ulcer disease. Over 20 years ago, antibiotics were shown useful in the treatment of ulcers because they killed or reduced H. pylori levels. It took nearly 15 years for the medical community to widely embrace this concept; they would promote H2 blockers like Tagamet and Zantac to treat ulcers. Once they accepted the concept the drug companies jumped on board to show that their drugs and the newer proton pump inhibitors like Prilosec and Prevacid worked really terrific with the antibiotics to treat ulcers.

Sounds to me pretty much like the same story all over again. Interestingly though with ulcer antibiotics, like any drug, are not the ultimate solution for ulcers. Read my comment in an earlier article to see my recommendations for ulcer treatment.

Related Articles:

Cardiovascular Benefits of Omega-3 Fats

Fish Oil Cuts Risk of Sudden Death

Drug Resistance Rising in Ulcer Bug

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