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Partying hard could lead to
harmful effects beyond a hangover, researchers suggest. Investigators
found that three healthy adults who developed meningitis, an infection
of the membranes surrounding the brain and spinal cord, may have contracted
it during a bout of binge drinking and smoking.
Meningitis is usually caused
by meningococcal bacteria, often a species known as Neisseria meningitidis.
The incidence of invasive meningococcal disease -- previously uncommon
in younger people -- rose among adolescents
and young adults in the 1990s. The findings indicate that binge
drinking and smoking, which have recently been shown to be
meningitis risk factors, could be behind this increase.
The three men, aged 18 to 21,
contracted the infection in May 1999. Public health investigators found
that all of the men had attended the same party, and that they were infected
with an identical strain of N. meningitidis, which strongly suggests -- but
does not confirm -- that they contracted the infection at the party.
Two of the patients recovered
with the aid of antibiotics and one died, the report indicates.
Upper respiratory tract infection
and crowding have long been known to be risk factors for meningitis. More
recently, other factors have also been linked to the disease, including
spending time in bars, binge drinking and smoking -- passive smoking as
well as active smoking.
The increased risk of
invasive meningococcal disease associated with bar patronage
is thought to be due to a combination of factors that could facilitate
transmission, including crowding, poor ventilation, active and passive
smoking, smoking-associated coughing, and the sharing of drinking glasses
and cigarettes.
Taken together, these findings
suggest that some of the recent increase in invasive meningococcal disease
may be due to modifiable risk factors.
A currently available vaccine
could probably have prevented the young men's infection, the researchers
note, as well as most other cases of meningococcal infection in this age
group.
Southern Medical Journal
2001;94:1192-1194
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